Genes that Escape Silencing on the Second X Chromosome May Drive Disease

When X-linked genes evade silencing on the “inactive” chromosome in XX cells, some protect women from diseases such as cancer, but others seem to promote conditions such as autoimmunity.

Chromosome compartments on the inactive X guide TAD formation independently of transcription during X-reactivation

Genes, Free Full-Text

X-Inactivation, Imprinting, and Long Noncoding RNAs in Health and Disease: Cell

Activation of Xist by an evolutionarily conserved function of KDM5C demethylase

X chromosome regions. Regions in the X chromosome are: Xp (short arm)

Epigenomes, Free Full-Text

Escaping but not the inactive X-linked protein complex coding genes may achieve X-chromosome dosage compensation and underlie X chromosome inactivation-related diseases - ScienceDirect

Escaping but not the inactive X-linked protein complex coding genes may achieve X-chromosome dosage compensation and underlie X chromosome inactivation-related diseases - ScienceDirect

IJMS, Free Full-Text

Genes that Escape Silencing on the Second X Chromosome May Drive Disease

Genes that Escape Silencing on the Second X Chromosome May Drive Disease